SYSTEMIC VS LOCALLY APPLIED ANTIBIOTICS

It is important to note that simply repackaging antibiotic powder designed for systemic application is a long way from meeting the requirements for our specialized local use of chemotherapeutic application in dentistry (locally applied antibiotic/LAA). Systemic antibiotics must meet a series of criteria  (pass thru multiple biological barriers, withstand the extreme acidity in the stomach, be contained in a time release pill or capsule that will dissolve at the appropriate location in the GI tract, etc) that have NO application to our locally applied dental end use. Our target is the periodontal pocket with an exact concentration that will produce the desired clinical result with the least amount to no side effects. In order to achieve this concentration in a periodontal pocket, it would take a toxic amount of systemic antibiotic. The localized use of P3 antibiotic formulas (LAA) bypasses all the side effects associated with systemic application (GI upset, skin rash with sunlight, and inability to consume dairy products, antiacids or anything else that contains Calcium).

P3 Dental Technologies uses the systemic powder as a starting point to begin the sophisticated proprietary processes of formulating specialized P3 products for localized dental use.