During oral, endodontic, implant and periodontal surgeries, it is very important to create a biologically friendly environment to encourage normal bone regeneration. P3 for Surgery provides these elements:
Physiological pH: Diseased dental surgical sites have an acidic pH which inhibits the osteogenic process of bone regeneration. P3 formulations are buffered to a normal 7.0 pH thus creating an environment conducive to bone regeneration.
Anticollagenase: The first step in bone regeneration is the formation of a collagen matrix which is subsequently mineralized to form mature bone. In a diseased dental surgical site, the high concentration of collagenase enzyme is rapidly breaking down the newly formed collagen produced by fibroblasts. P3 formulations are a potent neutralizer of the harmful enzyme collagenase.
Microbial Specificity: The antibiotic active ingredient in P3 for Surgery targets the pathogenic bacteria found in diseased dental surgical sites.
Calcium Supersaturation: In order to drive the osteogenic/osteoclastic equilibrium in the direction of osteogenesis, there must be a readily available source of free calcium in the surgical area. P3 formulas are supersaturated with calcium.
Substantivity: Because the antibiotic active ingredient in P3 has the ability to reversibly bind (not irreversibly bond) to alveolar bone and root surfaces, it is slowly released over an extended period to facilitate the normal physiological process of bone regeneration.
Proper Concentration: There is an exact concentration of antibiotic active ingredient that must be present to achieve the desired clinical results. As P3 clinicians, we know that during dental surgery it is very possible that there will be dilution of the formula by blood or irrigation. Therefore, P3 for Surgery has a higher concentration of antibiotic to allow for this possible dilution.
Summary: When atraumatic microsurgical techniques are employed at tissue level and followed by chemotherapeutic application of P3 at the cellular molecular levels, the stage is set for a successful surgical result, including regeneration of normal alveolar bone.